2. Cardiovascular system - guidance

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Use documents past their review date with Caution

BNF Section/s	Title	Issuing Body	Date of Issue/Review	Update Due
2.3.2.3	Andexanet alfa - Andexanet alfa for reversing anticoagulation from apixaban or rivaroxaban - TA697	NICE	12 May 2021
2.3.2 & 2.3.2.2 & Apixaban & Edoxaban	Anticoagulant prescribing - Kent And Medway ICB Position Statement And Risk Mitigation Principles For Anticoagulant Prescribing In Nvaf NHSE updated the Commissioning recommendations for national procurement for direct-acting oral anticoagulant(s) (DOACs) on the 6th of September 2024. This document will be reviewed ASAP, via the normal ICB governance process, to reflect the current NHSE recommendations.	Kent and Medway ICB	Apr 2024	Apr 26
2.3.2.2	Apixaban - Apixaban for the prevention of venous thromboembolism after total hip or knee replacement in adults TA245	NICE	Jan 2012	-
2.3.2 & 2.3.2.2	Atrial fibrillation - Atrial fibrillation: diagnosis and management NG196	NICE	Jun 2021	-
2.6	Bempedoic Acid/Ezetimibe - BEMPEDOIC ACID WITH EZETIMIBE (Nilemdo and Nustendi) for treating primary hypercholesterolemia or mixed dyslipidaemia. Implementation guidance for Nice TA694	Kent and Medway CCG	Sep 2021	Sep 2022
2.3.2.5	Dabigatran etexilate -Dabigatran etexilate for the prevention of venous thromboembolism after hip or knee replacement surgery in adults - TA157	NICE	Sept 2008	-
2.3.2.5	Dabigatran etexilate - Dabigatran etexilate for the prevention of stroke and systemic embolism in atrial fibrillation TA249	NICE	Jul 2021	-
2.5.3	Dapagliflozin & Empagliflozin - K&M Implementation of NICE TA’s – SGLT2 inhibitors (Dapagliflozin & Empagliflozin) in the treatment of chronic heart failure	Kent and Medway ICB	Aug 2023	Aug 2025
2.5.3	Dapagliflozin - Dapagliflozin for treating chronic heart failure with reduced ejection fraction TA679	NICE	Feb 2021	-
2.5.3	Dapagliflozin - Dapagliflozin for treating chronic heart failure with preserved or mildly reduced ejection fraction TA902	NICE	Jun 2023	-
2.5.3 6.3.1.4	Dapagliflozin - Dapagliflozin for treating chronic kidney disease TA775	NICE	Mar 2022	-
2.3.2.2	DOAC - Direct-acting oral anticoagulants (DOACs): paediatric formulations; reminder of dose adjustments in patients with renal impairment	MHRA Drug Safety Update	May 2023	-
2.3.2.2 2.3.2.5	DOAC Monitoring - DOAC Monitoring Recommendations for Non-Valvular Atrial Fibrillation (NVAF) in Primary Care	Kent and Medway CCG	Dec 2021	Dec 2023
2.5.3	Empagliflozin - Empagliflozin for treating chronic heart failure with reduced ejection fraction TA773	NICE	Mar 2022	-
2.5.3	Empagliflozin - Empagliflozin for treating chronic heart failure with preserved or mildly reduced ejection fraction TA929	NICE	Nov 2023
2.5.3	Empagliflozin - Empagliflozin for treating chronic kidney disease TA942	NICE	Dec 2023
2.3.1	Epoprostenol	*High-Cost Drugs*
2.5.1 6.3.1.4	Finerenone - Finerenone for treating chronic kidney disease in type 2 diabetes TA877	NICE	Mar 2023
2.6	Icosapent - Icosapent ethyl with statin therapy for reducing the risk of cardiovascular events in people with raised triglycerides TA805	NICE	13 July 2022
2.6	Inclisiran - Inclisiran for treating primary hypercholesterolaemia or mixed dyslipidaemia TA733	NICE	Oct 2021	2024
2.6	Inclisiran - Kent & Medway ICB Position Statement Prescribing Inclisiran (Leqvio®) for the treatment of primary hypercholesterolaemia or mixed dyslipidaemia in Kent and Medway	Kent and Medway ICB	Jul 2023	Jul 2025
2.6	Lipid Management - Summary of National Guidance for Lipid Management for Primary and Secondary Prevention of CVD	NICE /National Guidance	Mar 2024	-
2.4.1.4	Metolazone - MHRA Xaqua (metolazone) 5mg tablets: exercise caution when switching patients between metolazone preparations	MHRA Drug Safety Update	Jan 2023	-
2.4.1.4	Metolazone - Metolazone (Xaqua) prescribing position statement Version1.1	Kent and Medway ICB	Jun 2024	Jun 2026
2.4.1.4	Metolazone - Metolazone (Xaqua) Patient Information	Kent and Medway ICB	Jun 2024	Jun 2026
2.3.2.2	Rivaroxaban - Rivaroxaban for the prevention of venous thromboembolism after total hip or total knee replacement in adults - TA170	NICE	Apr 2009	-
2.3.2.2	Rivaroxaban - Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolism (PE) TA261	NICE	Jul 2012	-
2.5.2	Sacubitril + Valsartan - Sacubitril + Valsartan prescribing Guidance	MCH/Medway & Swale CCG	Sep 2016	-
2.5.3 6.3.1.4	SGLT2 - SGLT2 inhibitors for Chronic Kidney Disease (CKD) in Adults	Kent and Medway ICB	Jun 2024	Jun 2026
2.3.2.6	Warfarin - Guidance for switching from Warfarin to DOACs -	Kent and Medway CCG	Jun 2020	-

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