2.3.2.2 Factor Xa inhibitors

For Kent and Medway DOAC Monitoring Recommendations for Non-Valvular
Atrial Fibrillation (NVAF) in Primary Care Click Here

For SPS Guidance on Apixaban, Rivaroxaban and Edoxaban monitoring in Adults in Primary Care please Click Here

MHRA Drug Safety Update - Direct-acting oral anticoagulants (DOACs): paediatric formulations; reminder of dose adjustments in patients with renal impairment Click Here

For NICE Guideline NG196 Atrial Fibrillation: diagnosis and management April 2021 Click Here

Direct Oral Anticoagulants (DOACs) are recommended as first line treatment over Vitamin K
antagonists (warfarin) for treatment in newly initiated patients with non-valvular atrial fibrillation (NVAF) as per NICE NG196

Edoxaban is recommended as first line (preferred) DOAC in newly diagnosed patients with NVAF,
unless contraindicated, not tolerated or clinically inappropriate.

For NICE NG 196 and Kent & Medway Position Statement Click Here

For Reversal Agents Click Here